Mayo Clinic Preventive Medicine and Public Health Board Review (Mayo Clinic Scientific Press)


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Evidence-Based Medicine and the Changing Nature of Healthcare: 2007 IOM Annual Meeting Summary.

Be the first to write a review. Sorry, the book that you are looking for is not available right now. Description Table of Contents Product Details Click on the cover image above to read some pages of this book! Industry Reviews "The new text, Mayo Clinic Preventive Medicine and Public Health is a welcome addition to the library of any public health professional and most primary care practitioners. Biostatistics I: Basic Concepts M.

Thompson, MD 6. Immunization Claudia L.

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Maternal and Child Health Heidi K. Brost, MD 9. Limburg, MD Thompson, MD, and Darryl S.

Chutka, MD Injury Prevention and Control Kodjo M. Dan is the husband of Brittany Maynard, who died in November from a brain tumor. The couple moved from California to Oregon, one of five states that has authorized medical aid in dying in order for Brittany to have the option of a gentle dying process. Dan advocates for improving end-of-life care and options for terminally ill individuals.

His efforts were instrumental in securing the passage of the legislation in California, and his work now continues in the other states across the country. Andrew Horn is a serial social entrepreneur based in Brooklyn, NY. In just three years, he established the organization as one of the premiere adaptive athletic providers in Washington, D.

He is on a deep mission to spread gratitude around the globe and already has tens of thousands of people using the site. A lifelong activist for creating healing experiences for patients, families and the entire healthcare team, Wendy Leebov is internationally respected as a thought leader, healthcare executive, culture change strategist, coach, and author who has helped hospitals, health systems, and medical practices to achieve breakthroughs in the patient and family experience.

Before making her mark as champion of the international patient experience movement, Wendy was Vice President and change coach for the Albert Einstein Healthcare Network in Philadelphia where she worked for 20 years.

A self-described communication fanatic, Leebov has written 14 books on the patient experience, leadership, and service excellence. Carla Rotering. Her latest book with Carla Rotering, M. Wendy also serves on the Executive Board of the Beryl Institute. Wendy is a breast-cancer survivor and has been a watchful and engaged family member through the prolonged, life-threatening illnesses of her sister, mother, and friends. A bestselling author and hands-on consultant, Micah Solomon specializes in building stellar, profitable customer experiences, company culture, 21st-century marketing, and social and anti-social!

His latest business bestseller, High-Tech, High-Touch Customer Service, as well as his perennial bestseller, Exceptional Service, Exceptional Profit, a collaboration with the creators of the modern-day Ritz-Carlton have won multiple awards. His expertise has been featured in Inc.

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Mechanism of action: disrupts bacterial DNA 2. Includes most anaerobic microorganisms, including Bacteroides species drug of choice b. Exceptions include some anaerobic gram-positive organisms, including Peptostreptococcus, Actinomyces, and Propionibacterium acnes c. A drug of choice for C difcile, Entamoeba histolytica, Giardia, and Gardnerella 3. Include nausea, vomiting, reversible neutropenia, metallic taste, and a disulram reaction when coadministered with alcohol b.

Neuropathies and seizures with high doses 4. Major route of elimination: hepatic metabolism N. Quinupristin-Dalfopristin Synercid 1. Mechanism of action: block protein synthesis the 2 components are synergistic by binding to the 50S ribosomal subunit 2.

Mayo Clinic Preventive Medicine and Public Health Board Review - oi

Good activity against gram-positive cocci, including vancomycin-resistant Enterococcus faecium and staphylococcus and methicillin-resistant strains b. Substantially decreased activity against Enterococcus faecalis 3. Include a relatively high rate of inammation and irritation at the infusion site, arthralgias, myalgias, and hyperbilirubinemia b.

Inhibits the metabolism of other drugs metabolized through the CYP3A4 enzyme; guard against possible drug interactions 4. Major route of elimination: hepatic O. Linezolid 1.

Mechanism of action: inhibits bacterial ribosome assembly thus inhibits protein synthesis. Active against gram-positive bacteria, including methicillin-resistant staphylococci, most vancomycin-resistant enterococci, and penicillin-resistant S pneumoniae b. Active against Nocardia and some mycobacterial species 3. Most prominent: myelosuppression, especially with prolonged use b. Headache, diarrhea, and peripheral or optic neuropathy can occur c.

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Rare: lactic acidosis d. Linezolid is a weak monoamine oxidase inhibitor that interacts with some medications, such as selective serotonin reuptake inhibitors and monoamine oxidase inhibitors there are reports of serotonin syndrome 4. Major route of elimination: hepatic metabolism P.

Daptomycin 1. Mechanism of action: acts on cell membrane, causing rapid membrane depolarization and a potassium ion efux, which is followed by arrest of DNA, RNA, and protein synthesis, resulting in bacterial cell death 2. Spectrum of activity: gram-positive organisms, including Staphylococcus including methicillin-resistant strains , group A streptococcus, and Enterococcus including many vancomycin-resistant strains, but not well studied for serious infections 3.

Include GI effects, hypersensitivity reactions, headache, insomnia, myalgias, and creatine phosphokinase elevations b. The manufacturer suggests stopping use of statins during daptomycin therapy and monitoring creatine kinase values weekly 4. Major route of elimination: renal Q. Colistimethate or Colistin 1. Given IV or by inhalation for local effect in the lungs 2. Mechanism of action: colistimethate is converted to colistin, which disrupts the permeability of the bacterial membrane, leading to leakage of the cell contents and cell death 3.

Broad activity against gram-negative aerobes, including many multidrug resistant Acinetobacter baumannii, P aeruginosa, and Klebsiella pneumoniae. Its activity against resistant organisms has led to a resurgence in its use 4. Administered IV 1 Nephrotoxicity is the predominant adverse effect usually reversible but is less common than previously thought 2 Neurotoxicity rare includes paresthesias, vertigo, and possible neuromuscular blockade b. Administered by inhalation not FDA approved 1 FDA reported a possible connection between use of premixed colistimethate and death of a cystic brosis patient 2 Colistimethate should be reconstituted as close to the administration time as possible 5.

Requires dose adjustment of IV formulation with renal dysfunction II. Antiviral Agents A. AntiHerpes Simplex Agents 1.

How to Ace the CV Board Exam by Joseph G. Murphy, M.D.

Agents: acyclovir, valacyclovir, and famciclovir 2. Mechanism of action: activated by viral thymidine kinase and blocks viral DNA synthesis 3.

Mayo Clinic Preventive Medicine and Public Health Board Review

Not effective for treatment of cytomegalovirus CMV 4. Acyclovir has been associated with neurotoxicity and nephrotoxicity IV, especially if dose not adjusted for renal dysfunction b. GI effects c. Patients receiving high doses of acyclovir IV should be well hydrated to minimize renal tubule drug precipitation d. Famciclovir is associated uncommonly with headache, nausea, diarrhea, and rare CNS effects, specically confusion or hallucinations; neutropenia and liver function test elevations may occur rarely 5.

Major route of elimination: renal B. Anti-CMV Agents 1. Agents: ganciclovir, valganciclovir, cidofovir, and foscarnet 2. Mechanism of action a.


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Cidofovir: metabolized intracellularly by thymidine kinase for herpesvirus and by. Ganciclovir and valganciclovir: intracellularly phosphorylated; inhibit viral DNA synthesis c. Foscarnet: directly inhibits viral DNA synthesis; does not require phosphorylation 3. Ganciclovir and valganciclovir 1 Myelosuppression generally neutropenia or thrombocytopenia 2 Less common: nephrotoxicity, liver function test elevations, and fever 3 Rare: CNS effects, including headache, confusion, seizures, and coma b.

Cidofovir 1 Dose-related nephrotoxicity, neutropenia, iritis, uveitis, and GI effects 2 Saline hydration and probenecid should be used to decrease the risk of nephrotoxicity 3 Avoid use if possible in patients with renal dysfunction c. Foscarnet 1 Nephrotoxicity minimize with saline hydration , electrolyte disturbances, and CNS effects 2 Fever, nausea, vomiting, and diarrhea are common 5.

Major route of elimination: renal C. AntiInuenza Virus Agents 1.

Mayo Clinic Preventive Medicine and Public Health Board Review (Mayo Clinic Scientific Press) Mayo Clinic Preventive Medicine and Public Health Board Review (Mayo Clinic Scientific Press)
Mayo Clinic Preventive Medicine and Public Health Board Review (Mayo Clinic Scientific Press) Mayo Clinic Preventive Medicine and Public Health Board Review (Mayo Clinic Scientific Press)
Mayo Clinic Preventive Medicine and Public Health Board Review (Mayo Clinic Scientific Press) Mayo Clinic Preventive Medicine and Public Health Board Review (Mayo Clinic Scientific Press)
Mayo Clinic Preventive Medicine and Public Health Board Review (Mayo Clinic Scientific Press) Mayo Clinic Preventive Medicine and Public Health Board Review (Mayo Clinic Scientific Press)
Mayo Clinic Preventive Medicine and Public Health Board Review (Mayo Clinic Scientific Press) Mayo Clinic Preventive Medicine and Public Health Board Review (Mayo Clinic Scientific Press)
Mayo Clinic Preventive Medicine and Public Health Board Review (Mayo Clinic Scientific Press) Mayo Clinic Preventive Medicine and Public Health Board Review (Mayo Clinic Scientific Press)

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